By I. Lane Wong, M. D., F.A.C.O.G., Reproductive Endocrinology & Infertility “Unexplained Infertility” has been described as “a misfortune due to laws of chance or limitations of our knowledge.”  It is a diagnosis of exclusion, meaning the diagnosis is made after a standard evaluation of a couple fails to provide an explanation for their infertility.  What constitutes a standard evaluation is debatable. However, most experts agree for the female partner it includes a history, exam, assessment of ovulation, hysterosalpingogram (radiological study of the uterine cavity and tubes) and often laparoscopy (surgical visualization of the pelvis by placement of a narrow scope into the abdomen).

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