Posts Tagged ‘embryo donation’

The disposition of unused frozen embryos

Tuesday, October 19th, 2010

One difficult decision for many couples is how to dispose of unused frozen embryos once they have completed their families. This is true both for couples in which women are using their own eggs as well as those who use an egg donor.

A study reported in the October 2010 issue of Fertility & Sterility examines how both types of patient choose to deal with unused embryos in a private practice IVF center. A total of 1,262 patients using their own eggs had 5,417 embryos cryopreserved. A majority either used their embryos (39%) or continued storage (35%). Of 364 patients, who did not use their remaining 1,406 embryos, 77 (21%) donated 290 embryos to other infertile couples, 41 (11%) donated 160 embryos for research, and 246 (68%) discarded 956 embryos. In the same time period, 272 donor egg recipients had 1,233 embryos cryopreserved. A majority either used their embryos (40%) or continued storage (23%). Of 110 recipients that did not use their remaining 455 embryos, 62 (56%) donated 280 embryos to other infertile couples, 6 (6%) donated 31 embryos for research, and 42 (38%) discarded 144 embryos.

A higher proportion of patients using their own eggs ultimately used or stored their cryopreserved embryos for future reproduction compared with donor egg recipients. The interesting outcome is that egg donor recipients were much more likely to donate to other infertile couples and less likely to discard their remaining embryos compared with patients. I would guess that it's because the embryos created from donor eggs are not as strongly viewed as having a biological connection to the intended female parent and thus they feel more comfortable donating them to another couple.

How do fertility patients choose to dispose of unused embryos?

Wednesday, August 4th, 2010

IVF success rates have become so good that there are now many couples, especially those starting young, who find themselves with remaining frozen embryos after they have completed their family. Options for dealing with unused frozen embryos include discarding, donating them for research or donating them to another couple. Each ootion involves complex issues in making this difficult decision.

A survey in the July 2010 issue of Fertility & Sterility examined the choices made by parients at one fertility center. Of 149 patients from Washington University in St. Louis, 59% donated them to scientific research, 38% discarded, and 3% donated to a known or anonymous person/couple for attempted pregnancy. There was no significant difference in the choice selected between patients who achieved a pregnancy with delivery compared with those who did not.  In addition, the patient's age at retrieval and at the time of disposition as well as the total time in storage was not significantly different between patients electing to discard and those donating to research.

My experience at Reproductive Partners is that most couples avoid making this difficult decision and just keep their embryos frozen indefinitely. For highly successful couples the optiion of donating to another couple who has exhausted their options is a a way of giving something back when they have been so fortunate. But, as we can all understand, it can be difficult to have one's biologic offspring out there without having any knowledge or control of their future.

A few years ago there was an estimate of 400,000 frozen embryos in IVF centers throughout the United States, lending credability to the difficuty in making a decision to release them.