PCOS, Metformin and Infertility

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among women between the ages of 18 and 44, is a condition marked by abormal menstrual cycles and symptoms related to elevated androgens (male hormones) in females.such as excess body and facial hair, acne, difficulty getting pregnant, and patches of thick, darker, velvety skin. Associated conditions may include type 2 diabetes, …

Letrozole may be better than Clomid for women with PCOS

Letrozole (Femara) was associated with roughly a 42% increase in the pregnancy rate, compared with clomiphene citrate (Clomid) in infertile women with polycystic ovary syndrome in a double-blind, randomized study.

The pregnancy rate was 61.2% with letrozole versus 43% with clomiphene. There also was a trend toward more live births with letrozole (48.8% vs. 35.4%).

“We now have convincing evidence …