I contacted you a while ago about IVF My husband and I went through our first Round of IVF and it failed on multiple levels and looking for advice whether it was a protocol issues, something we did or just bad luck. iam 29 and my husband is 30
Here is our Story, We have been TTC for over 18 months I have PCOS and my husband has Severe MFI.
With my PCOS I seem to ovulate, i have periods regularly. I have recently had call my bloods done with. FSH 6.9, LH 5.1, Estrodol 44, AMH 3.65, AFC is 10-15 on each ovary so up to 30 total, prolactin 20.1, My testosterone was normal. My husband has low morphology and motility however 4-5 months ago has had the bilateral variocele repair surgery.
We opted for IVF has we had insurance coverage and fed up of the waiting and was told with both factors with us being young and with IcIS we could by pass the problems and had a 70% chance of success.
So for my IVF cycle I was on an angonst protocol of gonal f and menopour with cetrotide. base line fsh 6.9, e2 44 after 6 days of stims i had 20 follicles around 13-15 mm and e2 was 600. I started Cetrotide then and came back to the clinic 2-3 days later all 20 follicles were 18-21mm. I looked great on the US and all blood work normal. I triggered that night with ovidril has i was having increased pain and my RE was worried with OHSS risk and came back 35 hours later to have my ER.
This is where it all went wrong. With 20 follicles all measuring 20mm+ they only got 3 eggs ( they say there was no evidence of premature ovulation and all other follicles were empty). 2 of which were mature, Both Fertilized via IciS and we opted for a 3 day transfer instead of 5 due to the low number. An hour before the 3 day transfer the lab called to say they checked on the embryos and both embroyos had arrested and we were left with nothing to transfer. they embryos were 1 cell they didnt move passed fertilization we were told.
Apart from being devastated that at 29 i had no embryos to transfer after having what we thought was an excellent response to Stimulation. How can we prevent this happening, The lab did mention that maybe the egg quality was poor however at 29 i have a BMI of 25.1 however i am only 7 lbs away from normal BMI. I followed the protcol spot on, I exercise and eat well and I have been taking prenatal vit and supplements and acupuncture for the last year. I just dont want to have to go through this again, I am worried... was it they way I was stimmed?? was it the lab?? have you seen this response in someone "reproductively" young. I am scared that something is happening but no blood work is showing what. we are completely lost and want to try again but I need to make sure all mistakes are corrected. My RE has been great but all admitted this is extremely rare and has only seen it happen once before.
Any advice I know this was a long Post so I thank you for ur Time
Kind Regards
Very Upset and Frustrated IVF Patient.
