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Genetic testing

Posted: Sat Mar 21, 2015 10:52 am
by kiki13
Hello,

My husband and have gone though 1 cycle of IVF. our sperm was obtained by MESA, and we had 3 early miscarriages, (the fresh transfer lasted the longest). we are currently going through recombine and karyotype testing so far everything seems to be coming back okay, what else could be going wrong? Can the sperm itself be tested?

Thanks

Re: Genetic testing

Posted: Sat Mar 21, 2015 11:07 am
by Dr. Wisot
The most sensible course would be to do PGS on the embryos before transfer. A karyotype on you and your husband would make sure you are not translocation carriers.

If the embryos have normal karyotypes I do not know of anything you can do additionally to test the sperm.

Arthur L. Wisot, M. D.
Reproductive Partners Medical Group
Redondo Beach, California

Re: Genetic testing

Posted: Mon Mar 23, 2015 12:09 pm
by Dr. Wisot
Actually there is something else you can do to test the sperm- a Sperm Chromatin Structure Assay (SCSA) to test the fragmentation of the DNA.

Arthur L. Wisot, M. D.
Reproductive Partners Medical Group
Redondo Beach, California