Menopur only protocol and Dual Trigger.
Posted: Sun Oct 25, 2015 9:12 am
Dear Dr Wisot
Thank you for such great information. I had contacted you a while ago regarding some previous IVF attempts. I currently in the process of undergoing my IVF 4 and I changed Dr due to moving and just a new start this is my history.
Me 30 pcos, dh 32 male factor
Ivf 1- menopur/gonal f and cetrotide triggered with ovidril and got poor response 2 eggs despite have. 20 follicles on US . Nothing to transfer due two embyros arresting before day 3.
Ivf 2 - down regulated with lupron, gonal f and menopur triggered with 10,000 hcg 13 eggs collected 9 fertilized, 2 transferred and 4 frozen, bfn
Ivf 3 - FET transferred 2 expanded blasts and Bfn
My baseline blood work prior to ivf 4 : fsh 7.5, lh 6.9, estrogen 29, amh 3.3ng/ml, progestrone 0.7, (only abnormality was slightly elevated prolactin 40- which is being medicated to be reduced) AFC >10 on each side so in total > 20.
Ivf 4 - we are doing a fresh cycle - my re wants to change it up stim me with menopur ONLY and then trigger me with a dual trigger 10000 hcg first and 8000iu of lupron at 12 hours and another lupron again 12 later. I have tried to find research on both menopour only protocol and dual trigger..
Do you know the reasoning on why a dual trigger would be considered and what are the benefits of a dual trigger. I know I responded a lot better when I had the full hcg trigger verses ovidril. But I only find info on either hcg or lupron trigger not both. Is this a common procedure for repeated failure ivf. My re is also being very aggressive in supporting the leutal phase poster transfer with steroids, estrogen tables and patches and both progesterone in oil and progesterone insert.
I know you can't comment on a protocol per say but if u know of research and medical indications for these types of protocols that would be helpful I am just trying to find more info but I can't not seem to find it.
Thank you for a great discussion board.
Thank you for such great information. I had contacted you a while ago regarding some previous IVF attempts. I currently in the process of undergoing my IVF 4 and I changed Dr due to moving and just a new start this is my history.
Me 30 pcos, dh 32 male factor
Ivf 1- menopur/gonal f and cetrotide triggered with ovidril and got poor response 2 eggs despite have. 20 follicles on US . Nothing to transfer due two embyros arresting before day 3.
Ivf 2 - down regulated with lupron, gonal f and menopur triggered with 10,000 hcg 13 eggs collected 9 fertilized, 2 transferred and 4 frozen, bfn
Ivf 3 - FET transferred 2 expanded blasts and Bfn
My baseline blood work prior to ivf 4 : fsh 7.5, lh 6.9, estrogen 29, amh 3.3ng/ml, progestrone 0.7, (only abnormality was slightly elevated prolactin 40- which is being medicated to be reduced) AFC >10 on each side so in total > 20.
Ivf 4 - we are doing a fresh cycle - my re wants to change it up stim me with menopur ONLY and then trigger me with a dual trigger 10000 hcg first and 8000iu of lupron at 12 hours and another lupron again 12 later. I have tried to find research on both menopour only protocol and dual trigger..
Do you know the reasoning on why a dual trigger would be considered and what are the benefits of a dual trigger. I know I responded a lot better when I had the full hcg trigger verses ovidril. But I only find info on either hcg or lupron trigger not both. Is this a common procedure for repeated failure ivf. My re is also being very aggressive in supporting the leutal phase poster transfer with steroids, estrogen tables and patches and both progesterone in oil and progesterone insert.
I know you can't comment on a protocol per say but if u know of research and medical indications for these types of protocols that would be helpful I am just trying to find more info but I can't not seem to find it.
Thank you for a great discussion board.