pgd shows xxy

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jet2135
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pgd shows xxy

Post by jet2135 » Wed Aug 23, 2017 9:25 am

Hello,
One of our embryos came back xxy on a two probe done on day 3. However on day 5, it was an excellent looking hatching blast. What are the chances of a false positive and this is actually a normal embryo?
Thank you!

Dr. Wisot
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Joined: Fri Oct 14, 2005 11:16 am

Re: pgd shows xxy

Post by Dr. Wisot » Wed Aug 23, 2017 9:02 pm

There is no easy answer to this; it has many ramifications and is something that needs to be discussed with your doctor to understand all the implications.

The appearance of the blastocyst has nothing to do with the chromosomal make-up. In fact, aneuploid embryos sometime make the most beautiful blastocysts.

What is possible is that the embryo is a mosaic and this is not the predominant cell line. That's one of the problems with a Day 3 biopsy; you are testing just one cell of an eight cell embryo.

You will have to rely on your doctor's advice on how to proceed here.

Good luck.

Arthur L. Wisot, M. D.
Reproductive Partners Medical Group
Redondo Beach, California

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