Computers May Help Choose the Best Embryos for IVF

Researchers in Brazil are developing a new software tool that may help physicians and embryologists choose the best embryos for transfer after an IVF cycle.  The computer technology is supposed to recognize 24 characteristics of embryos, some of which are not detectable to embryologists using even the most sophisticated microscopes.  These characteristics include the size of the embryo, the texture of the image, as well as detailed biological characteristics relating to the number and similarity of cells in the embryo.

In their study of cattle embryos, the computer technology often had a higher success rate for finding viable embryos compared to embryologists.  The effectiveness of the technology has not yet been assessed on human embryos, but those studies seem to be underway.

This type of computer technology may provide us with a better non-invasive way to select the best embryos to transfer into a woman’s uterus in the future.  It does not however, replace preimplantation genetic screening (PGS) of embryos. The software program is unable to recognize if an embryo has genetic abnormalities.  Currently, the only way to do this is with PGS, which can be a key factor for embryo selection for some patients.

In the past, Reproductive Partners trialed a microscope and software program called Eeva that photographed cell division of embryos.  Eeva uses time-lapse imaging to photograph embryos throughout cell division. The software program then analyzes the information obtained to see if those embyros met the “milestones” necessary to become a viable embryo.  While it was interesting to see the way each embryo developed, we found that it did not enhance success rates. In addition, for embryo selection, PGS provided better results.

It’s always exciting to see the development of new technology for IVF.  Hopefully, this new software program will help improve IVF success rates and expedite the time to pregnancy for many patients in the future.