Tag Archives: in vitro fertilization

When Should ICSI be Used?

Written on October 13, 2017 at 10:20 am, by Dr. Marli Amin

Intracytoplasmic sperm injection (ICSI) is a very specialized technique performed by embryologists that involves injecting a single sperm into each egg retrieved from an IVF cycle.  It was first introduced in the early 1990s to help fertilize eggs for couples with male factor infertility.  Since the 1990s, the use of ICSI with IVF cycles has substantially increased.  In fact, ICSI …

The Role of Preimplantation Genetic Screening in IVF

Written on September 22, 2017 at 9:39 am, by Dr. Marli Amin

Over the past 2 decades, preimplantation genetic screening (PGS) has fallen in and out of favor among fertility specialists.  The benefits of performing PGS with in vitro fertilization have been hugely debated.  While the techniques and technology for PGS have advanced during this time, it’s still unclear whether PGS provides a benefit and that should be determined for each individual …

The Evolution of Fertility Treatment

Written on September 15, 2017 at 2:57 pm, by Dr. Marli Amin

This year marks the 50th anniversary of the U.S. Food and Drug Administration approving the sale and marketing of clomiphene citrate (Clomid) for the “treatment of ovulatory dysfunction in women desiring pregnancy”.   At the time, this was a huge breakthrough for couples who were desperate to conceive their own child.  For many patients, it was a “wonder drug”.

Prior to …

Flame Retardants May Decrease IVF Success

Written on September 4, 2017 at 7:48 am, by Dr. Marli Amin

A new study from Harvard T.H. Chan School of Public Health is showing that flame retardants may decrease the likelihood of pregnancy in women undergoing in vitro fertilization.  This is the first study to examine the association between organophosphate flame retardants (PFRs) and reproductive outcomes in women.

Urine samples from 211 women undergoing IVF between 2005 and 2015 at the …

Why Do Some Normal Embryos Fail to Implant?

Written on August 7, 2017 at 5:13 am, by Dr. Marli Amin

One of the hardest questions to answer for a fertility specialist is, “Why did a genetically normal embryo fail to implant?”.  With the increased use of preimplantation genetic screening on embryos, couples often have very high hopes of achieving a pregnancy when a genetically normal is obtained from an in vitro fertilization cycle. Unfortunately, not all genetically normal embryos will …

Computers May Help Choose the Best Embryos for IVF

Written on July 9, 2017 at 10:31 am, by Dr. Marli Amin

Researchers in Brazil are developing a new software tool that may help physicians and embryologists choose the best embryos for transfer after an IVF cycle.  The computer technology is supposed to recognize 24 characteristics of embryos, some of which are not detectable to embryologists using even the most sophisticated microscopes.  These characteristics include the size of the embryo, the texture …

Risk of Multiples with Fertility Treatment

Written on June 4, 2017 at 3:47 pm, by Dr. Marli Amin

On May 11, 2017, a couple in Virginia welcomed sextuplets after trying to conceive for 17 years.  This story made headlines in every major news outlet not only because of the number of babies born at one time, but also because of how long the couple had been trying to conceive.  While it’s definitely a happy occasion that this couple …

Why Women’s Fertility Declines with Age

Written on April 10, 2017 at 9:04 am, by Dr. Marli Amin

A new study out of Montreal Hospital Research Center is providing a new explanation for why women’s fertility declines with age.  The study compared the eggs of 6-12 week old mice to those of 60 week old mice.  They found that the microtubules in older eggs behave abnormally.  Microtubules help with chromosome segregation during cell division.  In older eggs, the …

Progesterone Treatment May Help Prevent Miscarriages

Written on January 12, 2017 at 2:02 pm, by Dr. Marli Amin

A new study shows that for women who have had multiple miscarriages, treatment with progesterone may help their chances of having a successful pregnancy.  This study, which was recently published in the journal Fertility and Sterility, showed that 68% of women who received progesterone supplementation went on to have a successful pregnancy compared to 51% who did not receive progesterone.…

More women in their 40s are having babies

Written on August 6, 2013 at 11:06 am, by Dr. Arthur Wisot FACOG

According to an article in the August 5th edition of the Los Angeles Times federal data show that women in their 40s are more likely to have babies now than at any time in more than four decades. Among American women ages 40 to 44, birthrates have hit their highest point since 1967, data recently released by the National Center …