The Evolution of Fertility Treatment

This year marks the 50th anniversary of the U.S. Food and Drug Administration approving the sale and marketing of clomiphene citrate (Clomid) for the “treatment of ovulatory dysfunction in women desiring pregnancy”.   At the time, this was a huge breakthrough for couples who were desperate to conceive their own child.  For many patients, it was a “wonder drug”.

Prior to …

Does Fertility Treatment Have Long Term Side Effects?

A new study published in the Canadian Medical Association journal reports a greater risk of heart failure and stroke in women who did not become pregnant after undergoing gonadotropin-based fertility treatment. The study looked at over 28,000 women, who underwent fertility treatment with injectable medications between 1993 and 2011 in Ontario, Canada.  Women who did not conceive with treatment had …

Good Fertility = Long Life

In a paper published in the Journal of Epidemiology and Community Health, a team of Swedish researchers report that having kids is associated with an increase in life expectancy, especially as we age. According to the new work, 60-year-old women with children had a remaining life expectancy of 24.6 years, compared with 23.1 years for those who do not have …

Prescription Medications Can Adversely Affect Male Fertility

Prescription medications can adversely affect male fertility.

Researchers at Stanford determined that certain classes of antihypertensive medications have a deleterious effect on male fertility. Using a national database of insurance claims filed in the US for patients with employer-provided coverage, they extracted data on men who had taken antihypertensive drugs, whose diagnosis or treatment codes suggested infertility. They compared the …

Conceiving with endometriosis-do you need IVF?

There is a very good review of the effects of endometriosis on fertility and the rationale for various types of treatment including surgery, injectable medications with IUI and eventually IVF.

Endometriosis creates an inflammatory environment in the pelvis and reproductive system, leading to the development of adhesions (scar tissues) and endometriomas (cysts known as chocolate cysts), which cause chronic pelvic …

ASRM ABSTRACTS: At older ages IUI rates closer to IVF

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.


RPMG’s Dr. Bill Yee has maintained that …

Is IVF the correct first treament for unexplained infertility?

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.


 Women over 38 with at least

How many IUIs to do? One or two?

This is a question that reproductive endocrinologists have studied and debated since the technique of intrauterine insemination was first developed.

A study reported in the September 2010 issue of Fertility and Sterility again looks at the effect of timing of an IUI on the success rate.

They divided the patients into three groups: patients in group 1 underwent a single preovulatory …

IVF or IUI for Women Over 40?

Selection of a treatment method for women over 40 whose main limitiation in conceiving is their age can be difficult. If they are in the "unexplained infertility" group with open tubes, no significant gynecologic problems and a partner with normal sperm parameters the common choices are to try injectable fertility drugs (COH) with artificial insemination (IUI) or in vitro fertilization …