How Genetic Testing Has Changed Fertility Treatment

As the technology for preimplantation genetic screening (PGS) of embryos has advanced over the past 10 years, it has changed the way we approach in vitro fertilization (IVF).  PGS involves genetically testing cells that have been biopsied from embryos made from an IVF cycle to make sure that the embyros we transfer into the uterus are chromosomally normal . PGS …

All Women Should be Offered Genetic Screening Prior to Pregnancy

The American College of Obstetricians and Gynecologists (ACOG) is recommending that all women, regardless of ethnic background, be offered genetic carrier screening prior to pregnancy.  In a new Committee Opinion, ACOG states “Carrier screening and counseling ideally should be performed before pregnancy because this enables couples to learn about their reproductive risk and consider the most complete range of reproductive …

Progesterone Treatment May Help Prevent Miscarriages

A new study shows that for women who have had multiple miscarriages, treatment with progesterone may help their chances of having a successful pregnancy.  This study, which was recently published in the journal Fertility and Sterility, showed that 68% of women who received progesterone supplementation went on to have a successful pregnancy compared to 51% who did not receive progesterone.…

Heparin may not help in recurrent pregnancy loss

Low-molecular-weight heparin (LMWH) does not increase ongoing pregnancy or live-birth rates in women with a viable pregnancy and unexplained recurrent pregnancy loss (RPL), according to a new study.

“Our data show that LMWH prescribed to women with unexplained RPL and a viable pregnancy does not increase live-birth rates. Moreover, our data show that any effect LMWH may have is minimal,” …

Fewer in vitro (IVF) multiple births in 2013 SART report

More than 1.5% of babies born in 2013 owe their lives to in vitro fertilization, and fewer of them were twins or triplets, according to new figures from the Society for Assisted Reproductive Technology.

A total of 63,286 babies were born as a result of 174,962 attempts to use assisted reproduction treatments, according to the report. Both figures represent small …

ASRM ABSTRACTS: More evidence for Day 5 biopsy for PGS for chromosomes

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.


Over the past several years preimplantation genetic …

ASRM ABSTRACTS: PGS shows promise in recurrent pregnancy loss

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.


Based on data from Day 3 embryo …

ASRM ABSTRACTS: Age, fertility, chromsomes and miscarriage

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.


There were two abstracts that emphasized the …

Recurrent miscarriage is caused mostly by abnormal chromosomes

In a study published in the October 2012 issue of Fertility & Sterility, results of preimplantation genetic screening (PGS) with comparative genomic hybridization (CGH) showed a significant decrease in the miscarriage rate in a group of patients with previous idiopathic recurrent pregnancy loss.

They analyzed a total of 2,282 embryos of which 35% were normal (euploid) and 60% were abnormal (aneuploid). …