Improving IVF success rates in women over 38 without increasing multiples

This is one of a series of news items from abstracts of studies presented at the Annual Meeting of the American Society for Reproductive Medicine as complied by Dr. David Meldrum, Scientific Director of Reproductive Partners. We appreciate the enormous amount of work it takes to compile and comment on these abstracts.

One of our greatest challenges has been

Rejuvenating Eggs From Older Women

Can this be true? It may be true, at least in mice.

A study being conducted in mice indicate that administering coenzyme Q10 to one-year old mice-the equivalent to women in their 40s-for three to four months significantly increased the number of ovulated eggs as well as the number of successful pregnancies. The treated mice also had an average of …

If you’re over 40 consider IVF first

Bypassing superovulation steps and proceeding directly to in vitro fertilization (IVF) technology appears to improve pregnancy outcomes for older women who have unexplained infertility, researchers reported at the annual meeting of the American Society for Reproductive Medicine.

This randomized trial found that older women with unexplained infertility were significantly more likely to achieve pregnancy and a live birth if treated …

IVF or IUI for Women Over 40?

Selection of a treatment method for women over 40 whose main limitiation in conceiving is their age can be difficult. If they are in the "unexplained infertility" group with open tubes, no significant gynecologic problems and a partner with normal sperm parameters the common choices are to try injectable fertility drugs (COH) with artificial insemination (IUI) or in vitro fertilization …

Does preimplantation genetic screening (PGS) improve IVF success rates in women over 35?

Some fertility centers promote preimplantation genetic screening as a way of improving IVF success rates in women over 35 (defining advanced maternal age).

Now a study in the January 2010 edition of Fertility & Sterility shows that PGS does not significantly improve implantation, pregnancy or live birth rates. In this randomized control study from Belgium, the clinical implantation rate per embryo …