The Role of Preimplantation Genetic Screening in IVF

Over the past 2 decades, preimplantation genetic screening (PGS) has fallen in and out of favor among fertility specialists.  The benefits of performing PGS with in vitro fertilization have been hugely debated.  While the techniques and technology for PGS have advanced during this time, it’s still unclear whether PGS provides a benefit and that should be determined for each individual …

Why Do Some Normal Embryos Fail to Implant?

One of the hardest questions to answer for a fertility specialist is, “Why did a genetically normal embryo fail to implant?”.  With the increased use of preimplantation genetic screening on embryos, couples often have very high hopes of achieving a pregnancy when a genetically normal is obtained from an in vitro fertilization cycle. Unfortunately, not all genetically normal embryos will …

Questions to Ask if Your IVF Cycle Fails

Although IVF has a high chance of success, not all couples conceive with their first IVF cycle.  Patients who don’t conceive with IVF often ask, “What happened?  Why weren’t we successful?”  These can be difficult questions to answer, but after an unsuccessful cycle, it’s important for both the patients and the physician to review how the cycle went.  For patients, …

Computers May Help Choose the Best Embryos for IVF

Researchers in Brazil are developing a new software tool that may help physicians and embryologists choose the best embryos for transfer after an IVF cycle.  The computer technology is supposed to recognize 24 characteristics of embryos, some of which are not detectable to embryologists using even the most sophisticated microscopes.  These characteristics include the size of the embryo, the texture …

Your Infertility and IVF Questions Answered Here…Free

Yes, that’s correct. You can ask a question about infertility or IVF and you will get a prompt answer. And it’s free. You do not have to be a patient of reproductive Partners or even a patient yet; you may just be starting your infertility journey and have not yet seen a doctor. This is a service that Reproductive Partners …

One Million IVF Babies and Counting

It seems like just yesterday: 1978 and the first IVF baby, Louise Brown, was born in England. In 1981 the first IVF baby was born in the U. S. Now there are over one million IVF babies in the U. S.

The latest report on in-vitro fertilization (IVF) and other assisted reproductive techniques (ART) from the American Society for Reproductive …

How Genetic Testing Has Changed Fertility Treatment

As the technology for preimplantation genetic screening (PGS) of embryos has advanced over the past 10 years, it has changed the way we approach in vitro fertilization (IVF).  PGS involves genetically testing cells that have been biopsied from embryos made from an IVF cycle to make sure that the embyros we transfer into the uterus are chromosomally normal . PGS …

How many embryos to transfer in IVF?

When we first started doing IVF in the 1980’s the state of the science, like culture techniques and only being able to sustain embryos in the lab until Day 2 or 3, required us to transfer multiple embryos to have any decent chance of success. One of the big problems we faced was the risk of high order multiple pregnancies. …

Making IVF More Successful. What works?

A recent article in Newsweek looks at “add-ons” to the basic IVF cycle and comes to the conclusion that there is no evidence that many of them help except the endometrial “scratch”: biopsy in the cycle before the transfer.

These add-ons include blastocyst culture, where the embryo is allowed to grow in the lab for five days instead of the …

All Women Should be Offered Genetic Screening Prior to Pregnancy

The American College of Obstetricians and Gynecologists (ACOG) is recommending that all women, regardless of ethnic background, be offered genetic carrier screening prior to pregnancy.  In a new Committee Opinion, ACOG states “Carrier screening and counseling ideally should be performed before pregnancy because this enables couples to learn about their reproductive risk and consider the most complete range of reproductive …