PGD test same abnormality


Re: PGD test same abnormality

Post by Cindy123 » Fri Dec 18, 2015 9:38 pm

Dr Wisot,
What causes the problem of aneuploidy? I have a normal karyotype test. Is it age related?
Thank you

Dr. Wisot
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Re: PGD test same abnormality

Post by Dr. Wisot » Sat Dec 19, 2015 11:12 am

It can be age related.

Each egg divides into the egg and polar body in a meiotic division which divides each chromosome pair. If they do not divide evenly this can result in too many or few chromsomes which results in trisomies or monosomies. The unequal division happens more frequently as a woman ages. :cry:

The same happens in the sperm which divides into two sperm with half the number of chromsomes.

Arthur L. Wisot, M. D.
Reproductive Partners Medical Group
Redondo Beach, California

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