Empty follicles -

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Claire155
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Joined: Thu Apr 07, 2016 8:51 am

Empty follicles -

Post by Claire155 » Thu Apr 07, 2016 8:59 am

Dear Dr,
I am 31 years old and my husband has been diagnosed with severe oligospermia (1.1M/ml & 33% progressive motility). He has bilateral varicoceles and was operated 6 months ago on the left one. This improved his sperm count slightly (it used to be 0.3M/ml with 12% prog. motility). His karyotype is normal (no Y chromosome microdeletion). On my side no issues where found although one of the gynecologists I consulted suspected a mild case of adenomyosis, my AMH is high. I also experience spotting every day in my luteal phase each month, with regular cycles and ovulation. We have now just had our 1st failed IVF ICSI cycle.
Here was our protocol:
Birth Control Pill for 1 month
Follitropin beta 200IU for 8 days (combined with Orgalutran on the last 2 days)
2x Ovitrelle 250 micrograms/0.5 mL on day 9
Sadly out of my 15 follicles only 3 oocytes where retrieved, all the others were empty. 2 oocytes fertilized and made it to grade 1 blastocysts on day 5 with no fragmentation. The transfer of both oocytes was done without ultrasound assistance.
I am now 8 days post transfer and have started menstruating yesterday.
I would be extremely grateful if you could provide your insight on any possible causes of our implantation failure and I welcome your recommendations for our next cycle.
Many thanks

Dr. Amin
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Posts: 56
Joined: Wed Mar 30, 2016 10:49 am

Re: Empty follicles -

Post by Dr. Amin » Tue Apr 12, 2016 4:49 pm

Implantation failure can happen for many reasons. Some of these include poor embryo quality, abnormal embryo genetics, and impaired endometrial receptivity, just to name a few. I recommend that you speak with your physician regarding your specific case to see if any issues can be identified. I wish you the best of luck with your next cycle.

Marli Amin, MD
Reproductive Partners Medical Group
Westminster, CA
Marli Amin, MD
Reproductive Partners Medical Group
Orange County, CA

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